3445-11-2

  • Product Name:N-(2-Hydroxyethyl)-2-pyrrolidone
  • Molecular Formula:C6H11 N O2
  • Purity:99%
  • Molecular Weight:129.159
Inquiry

Product Details;

CasNo: 3445-11-2

Molecular Formula: C6H11 N O2

Appearance: deep brown to yellow liquid

Buy Quality Hot Sale N-(2-Hydroxyethyl)-2-pyrrolidone 3445-11-2 Competitive Price

  • Molecular Formula:C6H11 N O2
  • Molecular Weight:129.159
  • Appearance/Colour:deep brown to yellow liquid 
  • Vapor Pressure:0.000152mmHg at 25°C 
  • Melting Point:19-21°C 
  • Refractive Index:n20/D 1.496(lit.) 
  • Boiling Point:140-142 ºC (3 mmHg) 
  • PKA:14.49±0.10(Predicted) 
  • Flash Point:100 ºC 
  • PSA:40.54000 
  • Density:1.143 
  • LogP:-0.46100 

N-(2-Hydroxyethyl)-2-pyrrolidone(Cas 3445-11-2) Usage

Chemical Properties

deep brown to yellow liquid

Uses

1-(2-Hydroxyethyl)-2-pyrrolidone can be used as co-solvent for agro, coating and inkjet formulations as well as a solvent for electronics processing.

Synthesis Reference(s)

Journal of the American Chemical Society, 74, p. 4959, 1952 DOI: 10.1021/ja01139a518

Flammability and Explosibility

Notclassified

InChI:InChI=1/C6H11NO2/c8-5-4-7-3-1-2-6(7)9/h8H,1-5H2

3445-11-2 Relevant articles

A biodegradable transdermal penetration enhancer based on N-(2-hydroxyethyl)-2-pyrrolidone I. Synthesis and characterization

W.J. Lambert a b, R.J. Kudla b, J.M. Holland c, J.T. Curry c

, International Journal of Pharmaceutics Volume 95, Issues 1–3, 30 June 1993, Pages 181-192

In the present report, model fatty acid esters of N-(2-hydroxyethyl)-2-pyrrolidone were synthesized in order to test this approach. It was found that a 2 order of magnitude increase in permeability for hydrocortisone through mouse skin could be achieved in vitro with these enhancers.

Correlating the Synthesis, Structure, and Catalytic Performance of Pt-Re/TiO2for the Aqueous-Phase Hydrogenation of Carboxylic Acid Derivatives

Haus, Moritz O.,Meledin, Alexander,Leiting, Sebastian,Louven, Yannik,Roubicek, Nico C.,Moos, Sven,Weidenthaler, Claudia,Weirich, Thomas E.,Palkovits, Regina

, p. 5119 - 5134 (2021/05/10)

Pt-Re bimetallic catalysts have many app...

Extending the chemical product tree: A novel value chain for the production of: N -vinyl-2-pyrrolidones from biogenic acids

Haus, Moritz Otto,Louven, Yannik,Palkovits, Regina

, p. 6268 - 6276 (2019/12/03)

The sustainable production of polymers f...

Method for Producing Bio-Based Homoserine Lactone and Bio-Based Organic Acid from O-Acyl Homoserine Produced by Microorganisms

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Paragraph 0232; 0233; 0234; 0235, (2014/10/16)

The present invention relates to a metho...

3445-11-2 Process route

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Conditions
Conditions Yield
With 5% active carbon-supported ruthenium; hydrogen; In water; at 150 ℃; for 6h; under 112511 Torr; Temperature; chemoselective reaction; Catalytic behavior; Green chemistry;
 
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Conditions
Conditions Yield
With Cp*RuCl(2-C5H4CH2NH2); hydrogen; sodium methylate; In isopropyl alcohol; at 100 ℃; for 23h; under 37503.8 Torr; Autoclave;
85%
With hydrogen; In 1,2-dimethoxyethane; at 70 ℃; for 48h; under 22502.3 Torr; chemoselective reaction; Autoclave; Molecular sieve;
 

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