77472-70-9
- Product Name：4-Phenyl-2-pyrrolidone-1-acetamide
- Molecular Formula：C12H14N2O2
- Purity：99%
- Molecular Weight：218.255
Product Details;
CasNo： 77472-70-9
Molecular Formula： C12H14N2O2
Quality Manufacturer Supply 99% Pure 4-Phenyl-2-pyrrolidone-1-acetamide 77472-70-9 Cheapest Price
- Molecular Formula:C12H14N2O2
- Molecular Weight:218.255
- Vapor Pressure:1.3E-09mmHg at 25°C
- Melting Point:129.5-130.5 °C(Solv: ethyl acetate (141-78-6))
- Refractive Index:1.579
- Boiling Point:486.4 °C at 760 mmHg
- PKA:15.67±0.40(Predicted)
- Flash Point:247.9 °C
- PSA：64.39000
- Density:1.22 g/cm3
- LogP:1.57540
4-Phenyl-2-pyrrolidone-1-acetamide(Cas 77472-70-9) Usage
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Description |
4-Phenyl-2-pyrrolidone-1-acetamide (also named as Phenylpiracetam, Fonturacetam) is a phenylated analog of the drug piracetam, which was developed in 1983 in Russia. It is now available as a prescription drug. It has antiamnesic, anticonvulsant and anxiolytic properties. It is used as a general stimulant or to increase tolerance to extreme temperatures and stress. |
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Uses |
Carphedone is a GABA derivative that exhibited apparent immunocorrection properties during immunosuppression induced by cyclophosphamide were studied. |
InChI:InChI=1/C12H14N2O2/c13-11(15)8-14-7-10(6-12(14)16)9-4-2-1-3-5-9/h1-5,10H,6-8H2,(H2,13,15)
77472-70-9 Relevant articles
Synthesis of substituted 2-(2-oxopyrrolidin-1-yl)acetamides
Kavina,Sizov,Yakovlev
, p. 873 - 878 (2017/08/02)
The reaction of chloroacetamide with 2 e...
Method for preparing phenyl piracetam
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Paragraph 0075; 0076; 0077; 0078; 0079; 0080-0088, (2017/05/09)
The invention discloses a method for pre...
SIMPLE METHODS FOR THE N-ALKYLATION OF LACTAMS
Kramarova, E. P.,Shipov, A. G.,Orlova, N. A.,Artamkina, O. B.,Belavin, I. Yu.,Baukov, Yu. I.
, p. 970 - 979 (2007/10/02)
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THE SYNTHESIS AND ANTISPASMODIC ACTIVITY OF 4-PHENYLPYRROLIDONE-2-ACETAMIDES
Glozman, O. M.,Morozov, I. S.,Zhmurenko, L. A.,Zagorevskii, V. A.
, p. 776 - 780 (2007/10/02)
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77472-70-9 Process route
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- 68497-63-2
methyl-2-oxo-4-phenylpyrrolidine-1-acetate
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- 77472-70-9
(RS)-2-(2-oxo-4-phenylpyrrolidin-1-yl)acetamide
| Conditions | Yield |
|---|---|
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With ammonium hydroxide; for 2h;
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81% |
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With ammonia; In methanol; at 20 - 30 ℃; for 12h; Concentration; Temperature; Solvent;
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81% |
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- 70291-40-6
2-oxo-4-phenyl-1-pyrrolidineacetic acid, ethyl ester
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- 77472-70-9
(RS)-2-(2-oxo-4-phenylpyrrolidin-1-yl)acetamide
| Conditions | Yield |
|---|---|
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With ammonia; In methanol; at 45 - 50 ℃; for 5h;
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100% |
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With ammonium hydroxide; for 2h;
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64% |
77472-70-9 Upstream products
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68497-63-2
methyl-2-oxo-4-phenylpyrrolidine-1-acetate
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70291-40-6
2-oxo-4-phenyl-1-pyrrolidineacetic acid, ethyl ester
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1198-97-6
4-phenylpyrrolidin-2-one
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106869-48-1
4-phenyl-1-(trimethylsilyl)-2-pyrrolidinone
77472-70-9 Downstream products
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1613318-02-7
C34H44N2O3
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