Product Details;
CasNo： 102483-16-9
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- Molecular Weight:0
coixan(Cas 102483-16-9) Usage
Coixan, derived from Job’s tears (Coix lacryma-jobi L.), is a plant-based compound rich in polysaccharides, including coixan A, B, and C, as well as other active ingredients. With a history of use in traditional Chinese medicine, coixan exhibits various pharmacological effects, including antioxidant, anti-inflammatory, antiaging, and immune-regulating properties. Studies reveal its potential in treating various conditions, such as diabetes, cancer, and inflammatory responses.
Genetic analysis of different Job’s tears germplasms indicates a high conservation of DNA sequences, with the GBSSI gene showing some variation. Coixan is found to be an efficient antioxidant, with variations in antioxidant activities among different germplasms. While no significant correlation is observed between antioxidant activity and geographical origin, a connection is noted with genetic diversity. The findings suggest the importance of heredity in understanding the antioxidant activity of coixan.
102483-16-9 Relevant articles
Coicis Semen for the treatment of malignant tumors of the female reproductive system: A review of traditional Chinese medicinal uses, phytochemistry, pharmacokinetics, and pharmacodynamics
Xue Pan, 1 , † Qian Shen, 2 , † Chuanlong Zhang, 2 Xiyuan Zhang, 3 Yi Li, 2 Zhuo Chang, 4 and Bo Pangcorresponding author 2 ,*
, Front Pharmacol. 2023; 14: 1129874.
Experimental studies have found that coixan can inhibit the progression of liver cancer and lung cancer . Based on the characteristics of the active ingredients contained in TCM preparations that exert anti-tumor effects, some studies have also designed and constructed appropriate nanoparticle or microparticle drug delivery systems by regulating the particle size, surface properties, drug carrier type, and other technical properties; such delivery systems could be used to overcome the low oral bioavailability of the polysaccharides contained in Coicis Semen, thereby enhancing the anti-tumor efficacy
Genetic differences and variation in polysaccharide antioxidant activity found in germplasm resources for Job’s tears (Coix lacryma-jobi L.)
Lingyan Xuan, Xiujie Xi, Zixian Xu, Huijun Xie, Yunguo Zhu, Zhou Cheng , and Shan Li
, Botany 23 June 2020
Coixan was shown to be an efficient antioxidant, and among the germplasms examined, the LNYX, FJPC, and AHBZ had the highest antioxidant activities.
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