What is the MITRAGYNINE PICRATE?

MITRAGYNINE PICRATE is , while it's Molecular Formula is C 23 H 30 N 2 O 4 . A neurochemical, having both stimulant and opiate-like effects depending on the dosage. Currently, Mitragynin is being investigated for its ability to treat hard drug addiction.

What is the CAS number for MITRAGYNINE PICRATE?

The CAS number of MITRAGYNINE PICRATE is 4098-40-2.

What is MITRAGYNINE PICRATE (4098-40-2) used for?

This alkaloid has been isolated from Mitragyna speciosa Korth, and is amorphous although it yields a series of crystalline salts and derivatives. The hydrochloride crystallizes as colourless leaflets from EtOH-Et20 with m.p. 243°C; the picrate forms thin, orange-red needles, m.p. 223-4°C and the methiodide is a pale yellow powder which, although amorphous, has a sharp melting point of 21 1. 5°C. The alkaloid also forms compounds with acetic acid, m.p. 142°C, decomposing at 175-6°, and with trichloroacetic acid, m.p. 157°C.Mitragynine exerts a general depressant effect on plain muscle and facilitates the passage of autonomic impulses. It is, however, ineffective against pathogenic organisms.InChI:InChI=1/C23H30N2O4/c1-5-14-12-25-10-9-15-21-18(7-6-8-20(21)28-3)24-22(15)19(25)11-16(14)17(13-27-2)23(26)29-4/h6-8,13-14,16,19,24H,5,9-12H2,1-4H3/b17-13+/t14-,16+,19+/m1/s1

Product classification

4098-40-2

Product Name：MITRAGYNINE PICRATE
Molecular Formula：C23H30 N2 O4
Purity：99%
Molecular Weight：398.502

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Product Details;

CasNo： 4098-40-2

Molecular Formula： C23H30 N2 O4

Factory Supply High Purity 99% 4098-40-2 MITRAGYNINE PICRATE with Efficient Shipping

Molecular Formula:C₂₃H₃₀N₂O₄
Molecular Weight:398.502
Vapor Pressure:1.39E-12mmHg at 25°C
Melting Point:92-95oC
Boiling Point:560.3°Cat760mmHg
PKA:18.35±0.60(Predicted)
Flash Point:292.7°C
PSA：63.79000
Density:1.22g/cm³
LogP:3.76300

MITRAGYNINE PICRATE(Cas 4098-40-2) Usage

Description	Mitragynine picrate is an alkaloid extracted from Mitragyna speciosa Korth. While it is amorphous in its natural state, it can form various crystalline salts and derivatives. The hydrochloride crystallizes as colorless leaflets with a melting point (m.p.) of 243°C, the picrate forms orange-red needles with an m.p. of 223-4°C, and the methiodide is an amorphous, pale yellow powder with a sharp melting point of 211.5°C. Additionally, mitragynine can form compounds with acetic acid (m.p. 142°C, decomposing at 175-6°C) and trichloroacetic acid (m.p. 157°C).
Chemical Properties	White to Off-White Solid
Uses	Mitragynine exhibits a general depressant effect on smooth muscle and aids the passage of autonomic impulses. While it lacks efficacy against pathogenic organisms, it functions as a neurochemical with stimulant and opiate-like effects, depending on the dosage. Currently, research is ongoing to explore the potential of mitragynine in treating hard drug addiction.

InChI:InChI=1/C23H30N2O4/c1-5-14-12-25-10-9-15-21-18(7-6-8-20(21)28-3)24-22(15)19(25)11-16(14)17(13-27-2)23(26)29-4/h6-8,13-14,16,19,24H,5,9-12H2,1-4H3/b17-13+/t14-,16+,19+/m1/s1

4098-40-2 Relevant articles

MITRAGYNINE ANALOGS FOR THE TREATMENT OF PAIN, MOOD DISORDERS AND SUBSTANCE USE DISORDERS

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Page/Page column 54; 60; 70, (2020/03/05)

The present invention provides a compoun...

THE MITRAGYNA SPECIES OF ASIA – Part IV. The alkaloids of the leaves of Mitragyna speciosa Korth.. Isolation of Mitragynine and Speciofoline1

A. H. Beckett, E. J. Shellard, A. N. Tackie

, Planta Med 1965; 13(2): 241-246

… sample of mitragynine picrate from the original mitragynine picrate prepared by In g and Ra … a sample of crystalline sdvated mitragynine obtained from the authentic mitragynine picrate. …

Synthetic and Receptor Signaling Explorations of the Mitragyna Alkaloids: Mitragynine as an Atypical Molecular Framework for Opioid Receptor Modulators

Kruegel, Andrew C.,Gassaway, Madalee M.,Kapoor, Abhijeet,Váradi, András,Majumdar, Susruta,Filizola, Marta,Javitch, Jonathan A.,Sames, Dalibor

, p. 6754 - 6764 (2016/06/14)

Mu-opioid receptor agonists represent ma...

4098-40-2 Process route

: C₂₅H₃₄N₂O₆

: 4098-40-2,4697-67-0,14382-79-7,14509-92-3,6202-22-8
mitragynine

Conditions

Conditions	Yield
With sodium tris(acetoxy)borohydride; acetic acid; In methanol; at 20 - 90 ℃; Inert atmosphere; Reflux;	100%

: C₂₂H₂₇N₂O₄^(1-)*Na⁽¹⁺⁾

: 77-78-1
dimethyl sulfate

: 6202-22-8
methyl (Z)-2-((2S,3S,12bS)-3-ethyl-8-methoxy-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl)-3-methoxyacrylate

: 4098-40-2,4697-67-0,14382-79-7,14509-92-3,6202-22-8
mitragynine