AICAR is tan powder, while it's Molecular Formula is C9H14N4O5. tan powder 5-Aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside is used as a cell permeable activator of AMP-activated protein kinase (AMPK), a metabolic master regulator that is activated in times of reduced energy availability (high cellular AMP:ATP ratios) and serves to inhibit anabolic processes. In vivo, pharmacologic activation of AMPK with AICAR mimics exercise and triggers insulin-independent glucose uptake by skeletal muscle.

Product classification

2627-69-2

Q: What is AICAR (2627-69-2) used for?

AICAR (2627-69-2) activates AMP-activated protein kinase (AMPK). Promotes ligand-independent activation of the insulin receptor.1 Promotes skeletal muscle autophagy via activation of FoxO3a.2 Controls smooth muscle cell hyperproliferation in vascular disease.3 ?Induces osteogenic differentiation in mesenchymal stem cells.4 Inhibits proinflammatory response in glial cells.5 Cell permeable.InChI:InChI=1/C9H14N4O5/c10-7-4(8(11)17)12-2-13(7)9-6(16)5(15)3(1-14)18-9/h2-3,5-6,9,14-16H,1,10H2,(H2,11,17)/t3-,5-,6-,9-/m1/s1

Product Name：AICAR
Molecular Formula：C₉H₁₄N₄O₅
Purity：99%
Molecular Weight：258.234

Inquiry

Product Details;

CasNo： 2627-69-2

Molecular Formula： C₉H₁₄N₄O₅

Appearance： tan powder

Quality Manufacturer Supply Top Purity AICAR 2627-69-2 Lowest Price. We supply high quality AICAR (CAS 2627-69-2), in stock, factory directly supply to clients, lower prices, more competitiveness.

What is the AICAR ?

5-Aminoimidazole-4-carboxamide ribonucleotide (AICAR) is a chemical compound that serves as an intermediate in the generation of inosine monophosphate. It is also known as AICA ribonucleotide or ZMP (5-aminoimidazole-4-carboxamide ribonucleotide). AICAR is an analog of adenosine monophosphate (AMP) and possesses the ability to stimulate AMP-dependent protein kinase (AMPK) activity.

What is the CAS number for AICAR ?

The CAS number of AICAR is 2627-69-2.

What is AICAR (2627-69-2) used for?

AICAR plays a vital role as an intermediate in the biosynthesis pathway of inosine monophosphate, which is an essential component in nucleotide synthesis. AICAR is capable of activating AMPK, a key cellular energy sensor enzyme that regulates various metabolic processes in response to cellular energy status.

Articles related to AICAR:

Article	Source
Interrogating the mechanism of a tight binding inhibitor of AIR carboxylase	Firestine, Steven M.,Wu, Weidong,Youn, Hasik,Jo Davisson , p. 794 - 803 (2009)
Synthesis of N-1 and ribose modified inosine analogues on solid support	Oliviero, Giorgia,Amato, Jussara,Borbone, Nicola,D'Errico, Stefano,Piccialli, Gennaro,Mayol, Luciano , p. 397 - 400 (2007)
AICAR inhibits cancer cell growth and triggers cell-type distinct effects on OXPHOS biogenesis, oxidative stress and Akt activation	Biochimica et Biophysica Acta (BBA) - Bioenergetics Volume 1807, Issue 6, June 2011, Pages 707-718

Quality Manufacturer Supply Top Purity AICAR 2627-69-2 Lowest Price

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