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Chemical Properties

Uses

Pharmaceutical Applications: 11α,16β,17,21-Tetrahydroxy-pregna-1,4-diene-3,20-dione finds extensive use in the pharmaceutical industry, particularly in the synthesis of corticosteroids and related medications. It serves as a key intermediate in the production of various corticosteroid drugs used for their anti-inflammatory, immunosuppressive, and metabolic effects.

Anti-inflammatory Medications: This compound, also known as 16α-hydroxyprednisolone, is utilized in the synthesis of medications with potent anti-inflammatory properties. These medications are often prescribed for the treatment of inflammatory conditions such as arthritis, asthma, dermatitis, and allergic reactions.

Immunosuppressive Agents: Certain corticosteroid drugs derived from 11α,16β,17,21-Tetrahydroxy-pregna-1,4-diene-3,20-dione are employed as immunosuppressive agents in the management of autoimmune disorders and to prevent organ rejection in transplant recipients.

Dermatological Treatments: Some formulations containing corticosteroids synthesized from this compound are utilized topically in dermatology for the treatment of various skin conditions, including eczema, psoriasis, and allergic dermatitis.

Research: In addition to its pharmaceutical applications, 11α,16β,17,21-Tetrahydroxy-pregna-1,4-diene-3,20-dione is also used as a research tool in studies investigating the mechanisms of action of corticosteroids and their potential therapeutic applications in various disease states.