
42553-65-1
- Product Name:Crocin
- Molecular Formula:C44H64O24
- Purity:99%
- Molecular Weight:976.978
Product Details;
CasNo: 42553-65-1
Molecular Formula: C44H64O24
Appearance: red crystals
Chinese Manufacturer Supply Best Quality Crocin 42553-65-1 Efficient Transportation
- Molecular Formula:C44H64O24
- Molecular Weight:976.978
- Appearance/Colour:red crystals
- Vapor Pressure:0mmHg at 25°C
- Melting Point:186° (effervescence)
- Refractive Index:1.641
- Boiling Point:1169 °C at 760 mmHg
- PKA:12.20±0.70(Predicted)
- Flash Point:337.7 °C
- PSA:391.20000
- Density:1.54 g/cm3
- LogP:-5.22520
Crocin(Cas 42553-65-1) Usage
Introduction |
Crocin (crocin) is also known as a-crocin and crocetin. It is a series of ester glycosides combining water-soluble carotenoids crocetin and different sugars. It is one of the main active ingredients of saffron, including crocin -1, crocin -2, crocin -3, crocin-4 and crocetin.It is centrally acting antihypertensive and can prevent atherosclerosis and be of antithrombosis, antiplatelet aggregation, and anti myocardial ischemia. |
Efficacy and effect |
The traditional medicine believes that the stigma croci can dredge and activate the collaterals, remove blood stasis, eradicate depression and relieve swelling and pain. It is mainly used for the treatment of anxiety depression, chest distention, irregular menstruation, postpartum haemorrhage and traumatic injury.?The main effective components are crocetin and crocin, which has many pharmacological activities, such as being anti-inflammatory and analgesic, antitumor, antidepressant, hypoglycemic and lowering blood pressure. Because the water solution of stigma croci is bright yellow with sweet smell, it is often used as a food additive and high-grade edible pigment, but also can be used as high dye for silk, cotton and wool products. In recent years, pharmacological researches indicate that stigma croci has good control effect for a variety of diseases, including cancer, coronary heart disease, atherosclerosis and hyperlipidemia. |
Pharmacological effects |
Crocin has the effect of the anti-inflammation and treatment of soft tissue injury, gall liver protection, anti-tumor and other pharmacological effects. It is widely used in food, medicine, chemical industry and other industries. It is used in the treatment of patients with cardiovascular disease and fatty liver.with good medicinal value. |
Description |
Crocin/Gardenia Extract is a Gardenia extract that contains crocin I, II, and III, and crocetin, among other compounds. |
Chemical Properties |
Solid |
Uses |
Crocin, is a natural carotenoid derived the flowers crocus and gardenia. Crocin has been shown to be a potent antioxidant. It has also been shown to have an antiproliferative action against cancer cells in vitro, and also possessing possible antidepressant properties. |
General Description |
A highly unsaturared diterpene dicarboxylic acid ester found in saffron. |
Biochem/physiol Actions |
Crocin alleviates some ethanol-induced impairments of learning and prevents ethanol-induced inhibition of hippocampal long-term potentiation (LTP), a form of activity-dependent synaptic plasticity that may underly learning and memory. Related CNS effects are specific to the digentiobiose ester; crocetin glucose gentiobiose ester is half as potent, and the diglucose ester has no effect at all. |
Who Evaluation |
Evaluation year: 1985 |
InChI:InChI=1/C46H68O23/c1-21(12-8-14-23(3)25(5)18-62-43-40(59)36(55)32(51)28(67-43)19-63-44-38(57)34(53)30(49)26(16-47)65-44)10-6-7-11-22(2)13-9-15-24(4)42(61)69-46-41(60)37(56)33(52)29(68-46)20-64-45-39(58)35(54)31(50)27(17-48)66-45/h6-15,26-41,43-60H,5,16-20H2,1-4H3/b7-6+,12-8+,13-9+,21-10-,22-11+,23-14-,24-15+/t26-,27-,28-,29-,30-,31-,32-,33-,34+,35+,36+,37+,38-,39-,40-,41-,43-,44-,45-,46+/m1/s1
42553-65-1 Relevant articles
SINGLET OXYGEN REACTIONS IN AQUEOUS SOLUTION. PHYSICAL AND CHEMICAL QUENCHING RATE CONSTANTS OF CROCIN AND RELATED CAROTENOIDS
Manitto, Paolo,Speranza, Giovanna,Monti, Diego,Gramatica, Paola
, p. 4221 - 4224 (2007/10/02)
Thermal decomposition of 3-(1,4-epidioxy...
13-cis-Crocin: A new Crocinoid of Saffron
Speranza, Giovanna,Dada, Giuseppe,Manitto, Paolo,Monti, Diego,Gramatica, Paola
, p. 189 - 192 (2007/10/02)
A new crocinoid isolated from saffron wa...
42553-65-1 Process route
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- 42553-65-1,91740-80-6
crocin

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- 42553-65-1,91740-80-6
cis-crocetin di(β-D-gentiobiosyl) ester
Conditions | Yield |
---|---|
With 3-(1,4-dihydro-1,4-epidioxy-4-methyl-1-naphthyl)propionic acid; In water; at 35 ℃; Rate constant;
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In water; at 20 ℃; for 1h; Irradiation;
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20 mg |
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- 42553-65-1,91740-80-6
crocin

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- 27876-94-4
crocetin
Conditions | Yield |
---|---|
crocin; With sodium hydroxide; water; at 50 ℃; for 3.5h;
With phosphoric acid; In water; at 20 ℃; for 3h;
|
|
With potassium hydroxide; at 65 ℃; for 2h;
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|
With potassium hydroxide; at 100 - 105 ℃;
|
|
With water; sodium hydroxide; at 100 ℃; for 3h;
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With water; sodium hydroxide; at 100 ℃; for 3h;
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0.6 g |
42553-65-1 Upstream products
-
42553-65-1
crocin
42553-65-1 Downstream products
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42553-65-1
cis-crocetin di(β-D-gentiobiosyl) ester
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27876-94-4
crocetin
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5892-54-6
Crocetindimethylester
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