10309-37-2

Description

Bakuchiol, extracted from the seeds and leaves of the babchi plant (Psoralea corylifolia), is a plant-based compound with a history of use in traditional Chinese and Indian Ayurvedic medicine. It shares skin benefits with retinol but is reputed to lack its side effects. The compound is known to stimulate collagen production, reduce fine lines and wrinkles, improve skin texture and radiance, and even out skin tone. Users may experience initial improvements within 4 to 6 weeks, with more pronounced results, such as improved wrinkles, firmness, and pigmentation, requiring longer-term use.

Uses

Studies indicate that Bakuchiol, specifically the (S)-Bakuchiol variant found in Psoralea glandulosa, exhibits antifungal and anti-tumor effects. It has been identified as a potent cytotoxic agent with concentration-dependent growth inhibition against leukemia cancer cells. Bakuchiol, with the chemical formula [(1E,3S)-3-ethenyl-3,7-dimethyl-1,6-octadien-1-yl]phenol, belongs to the Leguminosae plant family. Research has demonstrated its various pharmacological effects, including antioxidant, antibacterial, anti-inflammatory, antiaging, and estrogen-like properties. The compound offers protective effects in the heart, liver, skin, and other organs. It protects against ischemia-reperfusion injury in the heart, inhibits liver fibrosis, and has anticancer effects on various cancer cells. Bakuchiol also slows skin aging by preserving collagen, protects against bone loss, and reduces blood glucose and triglycerides, showing potential in protecting against pancreatic beta-cell damage and diabetes progression. The review emphasizes the pharmacological mechanisms and protective effects of Bakuchiol in human diseases, with a focus on its impact on the heart, liver, and other vital organs.

Safety Profile

Poison by intravenous andintraperitoneal routes. Moderately toxic by ingestion.When heated to decomposition it emits acrid smoke andfumes.