
148553-50-8
- Product Name:Pregabalin
- Molecular Formula:C8H17NO2
- Purity:99%
- Molecular Weight:159.228
Product Details;
CasNo: 148553-50-8
Molecular Formula: C8H17NO2
Appearance: off-white solid
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What is the Pregabalin ?
Pregabalin is off-white solid, while it's Molecular Formula is C8H17NO2. Pregabalin is an anticonvulsant drug used for neuropathic pain, as an adjunct therapy for partial seizures, and in generalized anxiety disorder. It was designed as a more potent successor to gabapentin. Pregabalin is marketed by Pfizer under the trade nam
What is the CAS number for Pregabalin ?
The CAS number of Pregabalin is 148553-50-8.
More information of Pregabalin 148553-50-8 are:
Synonyms |
Hexanoic acid, 3-(aminomethyl)-5-methyl-, (S)-;3-isobutyl GABA;(R-)-3-isobutyl GABA;CI 1008;PD 144723;CI-1008;Hexanoic acid, 3-(aminomethyl)-5-methyl-, (3S)-;Lyrica;Pregablin;(3S)-3-(aminomethyl)-5-methylhexanoic acid;(S)-(+)-3-Aminomethyl-5-methylhexanoic acid; |
CAS Number |
148553-50-8 |
Molecular Formula |
C8H17NO2 |
Molecular Weight |
159.228 |
Density |
0.997 g/cm3 |
Melting Point |
194-196 °C |
Boiling Point |
274 °C at 760 mmHg |
Flash Point |
119.5 °C |
HS CODE |
29224999 |
PSA |
63.32000 |
LogP |
1.78240 |
Pka |
4.23±0.10(Predicted) |
What is Pregabalin (148553-50-8) used for?
Pregabalin (Lyrica), an analog of GABA that is related to gabapentin, has been extensively studied in the treatment of GAD, fibromyalgia, neuropathic pain, and partial complex seizures.It appears to act even more selectively on the a2-δ subunit of calcium channels found in brain than does gabapentin. Pregabalin received FDA approval in late 2004 for use in treating neuropathic pain and epilepsy. In 2008, it became the first drug approved for the treatment of fibromyalgia.Even though prcgabalin reccived approval for the treatment of GAD in the European Union in 2006, the FDA has not approvedpregabalin for GAD in the United States as of this writing.With the consistent efficacy in clinical trials and the known safety of pregabalin in clinical expericnce, it is not completely clear what has held up approval of prcgabalin for GAD.There was reported concern of the risk-benefit ratio for the drug,given the hepatotoxicity seen in micc, but this has not proven to be a problem postrelease in humans. Pregabalin is categorized as an anticonvulsant and analgesic. The drug is under re-review currently by the FDA. Pregabalin has a potential for abuse and misuse. Pregabalin is regulated as a Schedule V compound in the United States.
InChI:InChI=1/C8H17NO2/c1-6(2)3-7(5-9)4-8(10)11/h6-7H,3-5,9H2,1-2H3,(H,10,11)/t7-/m0/s1
Articles related to Pregabalin:
Article |
Source |
Direct separation of pregabalin enantiomers using a zwitterionic chiral selector by high performance liquid chromatography coupled to mass spectrometry and ultraviolet detection |
Chennuru, Lakshmi Narayana,Choppari, Thirupathi,Nandula, Ramakrishna Prasad,Zhang, Tong,Franco, Pilar , (2016) |
Efficient Chemoenzymatic Synthesis of Optically Active Pregabalin from Racemic Isobutylsuccinonitrile |
Zhang, Qin,Wu, Zhe-Ming,Liu, Shuang,Tang, Xiao-Ling,Zheng, Ren-Chao,Zheng, Yu-Guo , p. 2042 - 2049 (2019) |
How to get the best price on Pregabalin?
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