What is the 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid hydrochloride?

1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid hydrochloride is white or light yellow crystalline powder, while it's Molecular Formula is C17H18FN3O3 . HCl. white or light yellow crystalline powder Ciprofloxacin hydrochloride is a fluoroquinolone antibiotic that is widely used as an antimicrobial and immunomodulatory agent. Its range of activity includes most strains of bacterial pathogens capable of inducing respiratory, urinary tract, gastrointestinal, and abdominal infections. It functions by inhibiting DNA gyrase (a type II topoisomerase) and topoisomerase IV, the enzymes responsible for negative supercoiling of chromosomes and DNA strand separation, thus blocking initiation of bacterial replication. Most recently Ciprofloxacin hydrochloride has been used in the management of postexposure inhalational anthrax and radiation combined injury resulting from nuclear disasters.[Cayman Chemical]

What is the CAS number for 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid hydrochloride?

The CAS number of 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid hydrochloride is 93107-08-5.

What is 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid hydrochloride (93107-08-5) used for?

Ciprofloxacin hydrochloride is the hydrochloride of ciprofloxacin, which is a synthetic second-generation quinolone antibacterial drug with broad-spectrum antibacterial activity and good bactericidal effect. It is 2 to 4 times stronger than enoxacin, and has antibacterial effects on Enterobacter, Pseudomonas aeruginosa, Haemophilus influenzae, Neisseria gonorrhoeae, Streptococcus, Legionella, and Staphylococcus aureus.InChI:InChI=1/C17H18FN3O3.ClH/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24;/h7-10,19H,1-6H2,(H,23,24);1H

What is the 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid hydrochloride?

1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid hydrochloride is white or light yellow crystalline powder, while it's Molecular Formula is C17H18FN3O3 . HCl. white or light yellow crystalline powder Ciprofloxacin hydrochloride is a fluoroquinolone antibiotic that is widely used as an antimicrobial and immunomodulatory agent. Its range of activity includes most strains of bacterial pathogens capable of inducing respiratory, urinary tract, gastrointestinal, and abdominal infections. It functions by inhibiting DNA gyrase (a type II topoisomerase) and topoisomerase IV, the enzymes responsible for negative supercoiling of chromosomes and DNA strand separation, thus blocking initiation of bacterial replication. Most recently Ciprofloxacin hydrochloride has been used in the management of postexposure inhalational anthrax and radiation combined injury resulting from nuclear disasters.[Cayman Chemical]

What is the CAS number for 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid hydrochloride?

The CAS number of 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid hydrochloride is 93107-08-5.

What is 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid hydrochloride (93107-08-5) used for?

Ciprofloxacin hydrochloride is the hydrochloride of ciprofloxacin, which is a synthetic second-generation quinolone antibacterial drug with broad-spectrum antibacterial activity and good bactericidal effect. It is 2 to 4 times stronger than enoxacin, and has antibacterial effects on Enterobacter, Pseudomonas aeruginosa, Haemophilus influenzae, Neisseria gonorrhoeae, Streptococcus, Legionella, and Staphylococcus aureus.InChI:InChI=1/C17H18FN3O3.ClH/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24;/h7-10,19H,1-6H2,(H,23,24);1H

Product classification

93107-08-5

Product Name：Ciprofloxacin HCl
Molecular Formula：C₁₇H₁₈FN₃O₃^.HCl
Purity：99%
Molecular Weight：367.808

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Product Details;

CasNo： 93107-08-5

Molecular Formula： C₁₇H₁₈FN₃O₃^.HCl

Appearance： white or light yellow crystalline powder

Buy Top Purity High Grade Ciprofloxacin HCl 93107-08-5 Cheap Price

Molecular Formula:C17H18FN3O3^.HCl
Molecular Weight:367.808
Appearance/Colour:white or light yellow crystalline powder
Melting Point:>300 °C
Boiling Point:581.8 °C at 760 mmHg
Flash Point:305.6 °C
PSA：74.57000
LogP:2.77910

Ciprofloxacin HCl(Cas 93107-08-5) Usage

Description	Ciprofloxacin hydrochloride is a synthetic second-generation quinolone antibacterial drug with potent bactericidal effects against various bacteria, including Enterobacter, Pseudomonas aeruginosa, Haemophilus influenzae, Neisseria gonorrhoeae, Streptococcus, Legionella, and Staphylococcus aureus. It inhibits bacterial DNA gyrase subunit A, preventing the cleavage and linking functions of the enzyme, thus hindering bacterial DNA replication. Ciprofloxacin differs from other quinolones due to a fluorine atom at the 6-position, a piperazine moiety at the 7-position, and a cyclopropyl ring at the 1-position.
Uses	Marketed as a broad-spectrum antibacterial agent, ciprofloxacin hydrochloride is highly effective against bacterial causes of enteritis. Additionally, it was the drug of choice for combating anthrax. Ciprofloxacin functions by inhibiting DNA gyrase and topoisomerase IV, crucial enzymes for bacterial replication. In radiation combined injury cases, it has shown immunomodulatory activities by reducing pro-inflammatory cytokines, inhibiting apoptosis and autophagy, and enhancing IL-3 production.
Brand name	Ciloxan (Alcon); Cipro (Bayer); Proquin (Esprit).
Biological Activity	FDA-approved for managing postexposure inhalational anthrax, ciprofloxacin demonstrates significant survival improvement in animals exposed to aerosolized Bacillus anthracis. In the USAMRIID rhesus monkey model, it achieves a maximum concentration (Cmax) of 1.74 μg/ml and a minimum concentration (Cmin) of 0.17 μg/ml, inhibiting the growth of B. anthracis with a MIC90 of 0.06 μg/ml.
references	[1]. fukumoto r, cary lh, gorbunov nv, et al. ciprofloxacin modulates cytokine/chemokine profile in serum, improves bone marrow repopulation, and limits apoptosis and autophagy in ileum after whole body ionizing irradiation combined with skin-wound trauma. plos one. 2013;8(3):e58389.[2]. drlica k, zhao x. dna gyrase, topoisomerase iv, and the 4-quinolones. microbiol mol biol rev. 1997 sep;61(3):377-92.[3]. meyerhoff a, albrecht r, meyer jm, et al. us food and drug administration approval of ciprofloxacin hydrochloride for management of postexposure inhalational anthrax. clin infect dis. 2004 aug 1;39(3):303-8.

InChI:InChI=1/C17H18FN3O3.ClH/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24;/h7-10,19H,1-6H2,(H,23,24);1H

93107-08-5 Relevant articles

Preparation method of quinolone carboxylic acid derivative or phthalazinone carboxylic acid derivative

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, (2021/10/27)

The invention belongs to the field of ph...

Advanced Continuous Flow Platform for On-Demand Pharmaceutical Manufacturing

Zhang, Ping,Weeranoppanant, Nopphon,Thomas, Dale A.,Tahara, Kohei,Stelzer, Torsten,Russell, Mary Grace,O'Mahony, Marcus,Myerson, Allan S.,Lin, Hongkun,Kelly, Liam P.,Jensen, Klavs F.,Jamison, Timothy F.,Dai, Chunhui,Cui, Yuqing,Briggs, Naomi,Beingessner, Rachel L.,Adamo, Andrea

, p. 2776 - 2784 (2018/02/06)

As a demonstration of an alternative to ...

Isolation and Characterization of Ciprofloxacin-HCL Crystals

A. P. Kakkar,Manmohan Singh &Arun Mendiratta

, Drug Development and Industrial Pharmacy Volume 23, 1997 - Issue 11

Three crystalline and one amorphous form of Ciprofloxacin-HCL were prepared and characterized by various instrumental techniques. The hygroscopicity, stability, and solubility of all the forms were also determined. Results indicated that all three crystalline and one amorphous form had distinctly different properties.

93107-08-5 Process route

: C₂₁H₂₃BFN₃O₇

: 93107-08-5,86483-48-9
ciprofloxacin hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride; In water; at 0 ℃; for 4h; pH=< 1;	92.4%

: 85721-33-1,178489-05-9,189257-90-7
ciprofloxacin

: 93107-08-5,86483-48-9
ciprofloxacin hydrochloride